Jezek Atlas on the Human Testis: Normal Morphology and Pathology

• Feature: contains a detailed description of the manipulation with the testicular biopsy (fixation, embedding, methods of staining etc.).
• Feature: richly illustrated normal spermatogenesis and various degrees of spermatogenesis disorders.
• Benefit: the reader will be able to estimate if there are chances for a successful spermatozoa extraction (TESE) despite the damaged spermatogenesis
• Feature: description of early detection of Ca in situ
• Benefit: the reader can introduce the appropriate IHC procedure/antibodies for Ca in situ
• Feature: the atlas will contain a detailed description of seminoma and non-seminoma tumours.
• Benefit: the reader will have a clear overview over the testicular neoplasms and their nature and prognosis
• Feature: new methods for the analysis of the testicular biopsy.
• Benefit: the reader will make himself familiar with new approaches of the analysis of the testicular tissue that could be routine methods in the future

The aim of this atlas is twofold:

• help experts in the area of reproductive medicine with correct interpretation of histological findings.
• Standardization of testicular biopsy analysis/procedures.

This book will present histological illustrative material from paraffin and semi-thin sections of the human testis. The afore-mentioned sections are routinely used in the assessment of testicular morphology. The early detection of cancer in situ is based on the careful morphological investigation of the biopsy and immunohistochemistry (IHC). Therefore, this atlas will contain a detailed description of IHC methods focusing on the detection of early malignant changes. In addition, extensive descriptions will be provided concerning testicular neoplasms and their IHC. Modern molecular biological methods such as in situ hybridization, DNA microarrays and proteomics related to the testicular biopsy will be presented.